Asymmetric Synthesis of Multisubstituted Dihydrobenzofurans by Intramolecular Conjugate Addition of Short-Lived C-O Axially Chiral Enolates.
نویسندگان
چکیده
Enantioselective intramolecular conjugate addition reactions of short-lived C-O axially chiral enolates have been developed. The reactions proceeded with inversion of the configuration and provided dihydrobenzofurans with contiguous tetra- and trisubstituted carbon centers in up to 96% enantiomeric excess (ee).
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 64 7 شماره
صفحات -
تاریخ انتشار 2016